ARG45170
anti-UGT1A6 antibody
anti-UGT1A6 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes UGT1A6 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | UGT1A6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human UGT1A6. |
| 偶联标记 | Un-conjugated |
| 別名 | UGT1A6; UDP glucuronosyltransferase family 1 member A6; UDP-glucuronosyltransferase 1-5; UDPGT 1-5; UGT1*5; UGT1-05; UGT1.5; UDP-glucuronosyltransferase 1-E; UGT-1E; UGT1E; UDP-glucuronosyltransferase 1A5; UGT1A5; GNT1; UGT1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 55-61 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | UGT1A6 |
| 全名 | UDP glucuronosyltransferase family 1 member A6 |
| 背景介绍 | This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008] |
| 生物功能 | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1. [UniProt] |
| 细胞定位 | Cell membrane; Endoplasmic reticulum membrane. [UniProt] |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | . [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45170 anti-UGT1A6 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45170 anti-UGT1A6 antibody at 2 ug/ml dilution.
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ARG45170 anti-UGT1A6 antibody WB image
Western blot: HEK293 stained with ARG45170 anti-UGT1A6 antibody at 0.5 μg/ml dilution.
