ARG46623
anti-UCMA antibody
anti-UCMA antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes UCMA |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | UCMA |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid synthetic peptide within the last 50 amino acids of human UCMA. |
| 偶联标记 | Un-conjugated |
| 別名 | upper zone of growth plate and cartilage matrix associated; UCMA; GRP; C10orf49; Unique cartilage matrix-associated protein; Gla-rich protein; Ucma-C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 19 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -673°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14BU0 Mouse Unique cartilage matrix-associated protein Swiss-port # Q8WVF2 Human Unique cartilage matrix-associated protein |
|---|---|
| 基因名称 | UCMA |
| 全名 | upper zone of growth plate and cartilage matrix associated |
| 背景介绍 | This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015] |
| 生物功能 | May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. [UniProt] |
| 细胞定位 | Secreted; Extracellular matrix. [UniProt] |
| 预测分子量 | 15 kDa |
