ARG56195
anti-UACA antibody [UACA/1222]
anti-UACA antibody [UACA/1222] for Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody [UACA/1222] recognizes UACA |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | UACA/1222 |
| 同位型 | IgG1, kappa |
| 靶点名称 | UACA |
| 抗原物种 | Human |
| 抗原 | Recombinant human UACA protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8CGB3 Mouse Uveal autoantigen with coiled-coil domains and ankyrin repeats Swiss-port # Q9BZF9 Human Uveal autoantigen with coiled-coil domains and ankyrin repeats |
|---|---|
| 基因名称 | UACA |
| 全名 | uveal autoantigen with coiled-coil domains and ankyrin repeats |
| 生物功能 | Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity). [UniProt] |
| 细胞定位 | Nuclear membrane |
| 预测分子量 | 163 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56195 anti-UACA antibody [UACA/1222] WB image
Western blot: A549 cell lysate stained with ARG56195 anti-UACA antibody [UACA/1222].
