ARG66985
anti-Tissue Factor antibody
anti-Tissue Factor antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Tissue Factor |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Tissue Factor |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within the extracellular domain of Human Tissue Factor. |
| 偶联标记 | Un-conjugated |
| 別名 | Thromboplastin; Tissue factor; TFA; CD142; TF; Coagulation factor III; CD antigen CD142 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | F3 |
| 全名 | coagulation factor III (thromboplastin, tissue factor) |
| 背景介绍 | This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| 生物功能 | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. [UniProt] |
| 预测分子量 | 33 kDa (unmodified); 45-50 kDa (glycosylated) |
检测图片 (5) Click the Picture to Zoom In
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ARG66985 anti-Tissue Factor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded human colorectal carcinoma tissue stained with ARG66985 anti-Tissue Factor antibody at 1:100 dilution.
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ARG66985 anti-Tissue Factor antibody FACS image
Flow Cytometry: Cells stained with ARG66985 anti-Tissue Factor antibody at 1:100 dilution.
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ARG66985 anti-Tissue Factor antibody WB image
Western blot: A431 cell stained withARG66985 anti-Tissue Factor antibody at 1:1000 dilution, overnight at 4°C.
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ARG66985 anti-Tissue Factor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded human breast carcinoma tissue stained with ARG66985 anti-Tissue Factor antibody at 1:100 dilution.
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ARG66985 anti-Tissue Factor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded human liver carcinoma tissue stained with ARG66985 anti-Tissue Factor antibody at 1:100 dilution.
