ARG63130

anti-Tissue Factor Pathway Inhibitor antibody

anti-Tissue Factor Pathway Inhibitor antibody for Western blot and Human

Cell Biology and Cellular Response antibody

概述

产品描述 Goat Polyclonal antibody recognizes Tissue Factor Pathway Inhibitor
反应物种 Hu
应用 WB
特异性 This antibody is expected to recognize isoform a (NP_006278.1) only.
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 Tissue Factor Pathway Inhibitor
抗原物种 Human
抗原 C-VKIAYEEIFVKNM
偶联标记 Un-conjugated
別名 TFI; Lipoprotein-associated coagulation inhibitor; LACI; EPI; TFPI1; Tissue factor pathway inhibitor; TFPI; Extrinsic pathway inhibitor

应用说明

应用建议
应用 推荐稀释比
WB0.3 - 1 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 7035 Human TFPI

Swiss-port # P10646 Human Tissue factor pathway inhibitor

背景介绍 This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]
研究领域 Cell Biology and Cellular Response antibody
预测分子量 35 kDa
翻译后修饰 O-glycosylated.

检测图片 (2) Click the Picture to Zoom In

  • ARG63130 anti-Tissue Factor Pathway Inhibitor antibody WB image

    Western Blot: 1). Mock transfection; 2) TFPI (RC219033) expressing plasmid transfected HEK293 cell lysate standed with ARG63130 anti-Tissue Factor Pathway Inhibitor antibody

  • ARG63130 anti-Tissue Factor Pathway Inhibitor antibody WB image

    Western Blot: HeLa lysate (RIPA buffer, 35 µg total protein cells per lane) stained with ARG63130 anti-Tissue Factor Pathway Inhibitor antibody at 0.3 µg/ml dilution.