ARG52445
anti-Thyroid Hormone Receptor alpha antibody [2103]
anti-Thyroid Hormone Receptor alpha antibody [2103] for Western blot and Human,Rat
Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [2103] recognizes Thyroid Hormone Receptor alpha |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Dog, NHuPrm |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 2103 |
| 同位型 | IgG1 |
| 靶点名称 | Thyroid Hormone Receptor alpha |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | c-ERBA-1; c-erbA-1; Thyroid hormone receptor alpha; V-erbA-related protein 7; AR7; NR1A1; Nuclear receptor subfamily 1 group A member 1; ERBA1; CHNG6; THRA1; THRA2; ERB-T-1; c-erbA-alpha; ERBA; EAR7; EAR-7 |
应用说明
| 应用建议 |
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| 应用说明 | Specific for the ~50k TR-α1 and the ~58k TR-α2 proteins. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | THRA |
| 全名 | thyroid hormone receptor, alpha |
| 背景介绍 | Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). |
| 研究领域 | Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 55 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52445 anti-Thyroid Hormone Receptor alpha antibody [2103] WB image
Western blot: Rat hippocampal lysate showing specific immunolabeling of the ~50 kDa TR-α1 and the ~58 kDa TR-α2 protein stained with ARG52445 anti-Thyroid Hormone Receptor alpha antibody [2103]
