ARG65187
anti-Themis antibody
anti-Themis antibody for Western blot and Mouse
Developmental Biology antibody; Immune System antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes Themis |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Themis |
| 抗原物种 | Mouse |
| 抗原 | C-EERTINLPKSLKSH |
| 偶联标记 | Un-conjugated |
| 別名 | C6orf207; C6orf190; SPOT; Thymocyte-expressed molecule involved in selection; bA325O24.3; Protein THEMIS; bA325O24.4; GASP; TSEPA |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Themis |
| 全名 | thymocyte selection associated |
| 背景介绍 | This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| 生物功能 | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody |
| 预测分子量 | 73 kDa |
| 翻译后修饰 | Phosphorylated on Tyr residues quickly after TCR stimulation. |
检测图片 (1) Click the Picture to Zoom In
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ARG65187 anti-Themis antibody WB image
Western Blot: Mouse Spleen lysate (35 µg protein in RIPA buffer) stained with ARG65187 anti-Themis antibody at 0.3 µg/ml dilution.
