ARG45084
anti-Themis antibody
anti-Themis antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Themis |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Themis |
| 抗原物种 | Human |
| 抗原 | Themis (N-terminal region) antibody was generated from a peptide that included amino acids in the N-terminal region of human themis. This sequence has high homology to the conserved region in rat and mouse themis. |
| 偶联标记 | Un-conjugated |
| 別名 | THEMIS; Thymocyte Selection Associated; C6orf190; C6orf207; THEMIS1; Thymocyte-Expressed Molecule Involved In Selection; Thymocyte Selection Pathway Associated; Protein THEMIS; BA325O24.4; BA325O24.3; FLJ40584; TSEPA; Thymocyte Expressed Molecule Involved In Selection; Signaling Phosphoprotein Specific For T Cells; Chromosome 6 Open Reading Frame 207; Chromosome 6 Open Reading Frame 190; GRB2-Associated Protein; GASP; SPOT |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | THEMIS |
| 全名 | Thymocyte Selection Associated |
| 背景介绍 | This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| 生物功能 | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. [Uniprot] |
| 细胞定位 | Cytoplasm, Nucleus. [Uniprot] |
| 预测分子量 | 74 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
