ARG23285
anti-Talin 2 antibody [53.8]
anti-Talin 2 antibody [53.8] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rabbit
概述
| 产品描述 | Mouse Monoclonal antibody [53.8] recognizes Talin 2 |
|---|---|
| 反应物种 | Hu, Ms, Rb |
| 应用 | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 53.8 |
| 同位型 | IgG2b |
| 靶点名称 | Talin 2 |
| 抗原物种 | Human |
| 抗原 | Recombinant Mouse Talin 2. (aa. 2300-2542) |
| 偶联标记 | Un-conjugated |
| 別名 | Talin-2; ILWEQ |
应用说明
| 应用建议 |
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| 应用说明 | ICC/IF: Methanol treatment is required prior to antibody staining. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TLN2 |
| 全名 | talin 2 |
| 背景介绍 | This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008] |
| 生物功能 | As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). [UniProt] |
| 预测分子量 | 272 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG23285 anti-Talin 2 antibody [53.8] ICC/IF image
Immunofluorescence: ARG23285 anti-Talin 2 antibody [53.8] used for immunofluorescent staining of isolated talin-1 null cells fixed in paraformaldehyde and permeablized with triton X-100.
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ARG23285 anti-Talin 2 antibody [53.8] IHC-Fr image
Immunohistochemistry: Frozen section of murine heart stained with ARG23285 anti-Talin 2 antibody [53.8].
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ARG23285 anti-Talin 2 antibody [53.8] WB image
Western blot: Recombinant talin1 and talin2 proteins stained with ARG23285 anti-Talin 2 antibody [53.8].
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ARG23285 anti-Talin 2 antibody [53.8] WB image
Western blot: Murine tissue lysates: Brain, heart, spleen, kidney, lung, liver and muscle lysates stained with ARG23285 anti-Talin 2 antibody [53.8].
