ARG46620

anti-TYW1 antibody

anti-TYW1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes TYW1
反应物种 Hu, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 TYW1
抗原物种 Human
抗原 A 19 amino acid synthetic peptide within the last 50 amino acids of human TYW1.
偶联标记 Un-conjugated
別名 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae); TYW1; TYW1A; RSAFD1; YPL207W; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -670°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 55253 Human TYW1

Swiss-port # Q9NV66 Human S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

基因名称 TYW1
全名 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
背景介绍 Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
生物功能 Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). [UniProt]
预测分子量 84 kDa