anti-TYK2 phospho (Tyr1054) antibody

anti-TYK2 phospho (Tyr1054) antibody for Western blot and Human,Mouse,Rat

Signaling Transduction antibody
publication_link 参考文献1


产品描述 Rabbit Polyclonal antibody recognizes TYK2 phospho (Tyr1054)
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 TYK2
抗原物种 Human
抗原 Peptide sequence around phosphorylation site of tyrosine 1054 (H-E-Y(p)-Y-R) derived from Human TYK2.
偶联标记 Un-conjugated
別名 JTK1; IMD35; Non-receptor tyrosine-protein kinase TYK2; EC


应用 推荐稀释比
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
缓冲液 PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 7297 Human TYK2

Swiss-port # P29597 Human Non-receptor tyrosine-protein kinase TYK2

基因名称 TYK2
全名 tyrosine kinase 2
背景介绍 TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
生物功能 Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. [UniProt]
研究领域 Signaling Transduction antibody
预测分子量 134 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG51647 anti-TYK2 phospho (Tyr1054) antibody WB image

    Western blot: Extracts from HT29 cells untreated(lane 1) or treated with Anisomycin(lane 2) stained with ARG51647 anti-TYK2 phospho (Tyr1054) antibody.


Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats.

WB / Rat

Zhang Yue-Zhu et al.
Biomed Environ Sci.,  (2019)