ARG42748
anti-TXNDC4 antibody
anti-TXNDC4 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TXNDC4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TXNDC4 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 57-406 of Human TXNDC4 (NP_055866.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Thioredoxin domain-containing protein 4; ERp44; Endoplasmic reticulum resident protein 44; PDIA10; TXNDC4; ER protein 44 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HepG2 | ||||
| 实际分子量 | ~ 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BS26 Human Endoplasmic reticulum resident protein 44 Swiss-port # Q9D1Q6 Mouse Endoplasmic reticulum resident protein 44 |
|---|---|
| 基因名称 | ERP44 |
| 全名 | endoplasmic reticulum protein 44 |
| 背景介绍 | This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016] |
| 生物功能 | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. [UniProt] |
| 细胞定位 | Endoplasmic reticulum lumen. [UniProt] |
| 预测分子量 | 47 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42748 anti-TXNDC4 antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG42748 anti-TXNDC4 antibody at 1:3000 dilution.
