ARG41502
anti-TSPO / PBR antibody
anti-TSPO / PBR antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TSPO / PBR |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TSPO / PBR |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human TSPO / PBR. |
| 偶联标记 | Un-conjugated |
| 別名 | DBI; BZRP; PBS; PBR; pk18; PKBS; mDRC; BPBS; IBP; Translocator protein; Mitochondrial benzodiazepine receptor; PTBR; MBR; Peripheral-type benzodiazepine receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| 阳性对照 | A431 | ||||||||||||
| 实际分子量 | ~ 17 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TSPO |
| 全名 | translocator protein (18kDa) |
| 背景介绍 | Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012] |
| 生物功能 | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. [UniProt] |
| 细胞定位 | Mitochondrion membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41502 anti-TSPO / PBR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon tissue stained with ARG41502 anti-TSPO / PBR antibody.
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ARG41502 anti-TSPO / PBR antibody WB image
Western blot: A431 cell lysate stained with ARG41502 anti-TSPO / PBR antibody.
