ARG55500
anti-TRPV5 antibody
anti-TRPV5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TRPV5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TRPV5 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human TRPV5 (NP_062815.3) |
| 偶联标记 | Un-conjugated |
| 別名 | ECaC1; OTRPC3; ECaC; CaT2; ECAC1; CAT2; TrpV5; Epithelial calcium channel 1; Transient receptor potential cation channel subfamily V member 5; Calcium transport protein 2; Osm-9-like TRP channel 3 |
应用说明
| 预测反应性说明 | Rat | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TRPV5 |
| 全名 | transient receptor potential cation channel, subfamily V, member 5 |
| 背景介绍 | This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008] |
| 生物功能 | Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity). [UniProt] |
| 研究领域 | Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 83 kDa |
| 翻译后修饰 | Glycosylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG55500 anti-TRPV5 antibody WB image
Western blot: HepG2 cell lysate stained with ARG55500 anti-TRPV5 antibody.
