anti-TRPS1 antibody [SQab30333]

anti-TRPS1 antibody [SQab30333] for IHC-Formalin-fixed paraffin-embedded sections and Human


产品描述 Recombinant rabbit Monoclonal antibody [SQab30333] recognizes TRPS1
反应物种 Hu
应用 IHC-P
宿主 Rabbit
克隆 Monoclonal
克隆号 SQab30333
同位型 IgG
靶点名称 TRPS1
抗原物种 Human
抗原 Synthetic peptide of Human TRPS1
偶联标记 Un-conjugated
Protein Full name Zinc finger transcription factor Trps1
別名 TRPS1, Transcriptional Repressor GATA Binding 1, LGCR, GC79, Tricho-Rhino-Phalangeal Syndrome Type I Protein, Zinc Finger Transcription Factor Trps1, Trichorhinophalangeal Syndrome I, Zinc Finger Protein GC79


应用 推荐稀释比
IHC-P1:50 - 1:100
应用说明 IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Beast cancer


形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05%BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.


基因名称 TRPS1
全名 Transcriptional Repressor GATA Binding 1
背景介绍 This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]
生物功能 Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. [UniProt]
细胞定位 Nucleus
预测分子量 141 kDa
翻译后修饰 Sumoylated. Sumoylation in the repressor domain inhibits the transcription repression activity. Sumoylation on Lys-1201 is the major site. Appears to be sumoylated on multiple sites. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG67048 anti-TRPS1 antibody [SQab30333] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded breast cancer stained with ARG67048 anti-TRPS1 antibody [SQab30333].