ARG63144

anti-TRPM7 / LTRPC7 antibody

anti-TRPM7 / LTRPC7 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse

Neuroscience antibody

概述

产品描述 Goat Polyclonal antibody recognizes TRPM7 / LTRPC7
反应物种 Hu, Ms
预测物种 Dog, Rat, Pig
应用 ICC/IF, IHC-P
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 TRPM7 / LTRPC7
抗原物种 Human
抗原 C-TKESESTNSVRLML
偶联标记 Un-conjugated
別名 Transient receptor potential cation channel subfamily M member 7; CHAK; ALSPDC; LTrpC7; LTRPC7; CHAK1; Channel-kinase 1; TRP-PLIK; EC 2.7.11.1; LTrpC-7; Long transient receptor potential channel 7

应用说明

应用建议
应用 推荐稀释比
ICC/IF10 µg/ml
IHC-P4 - 6 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 54822 Human TRPM7

GeneID: 58800 Mouse TRPM7

Swiss-port # Q923J1 Mouse Transient receptor potential cation channel subfamily M member 7

Swiss-port # Q96QT4 Human Transient receptor potential cation channel subfamily M member 7

背景介绍 The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.[provided by RefSeq, May 2010]
研究领域 Neuroscience antibody
预测分子量 213 kDa
翻译后修饰 Autophosphorylated.

检测图片 (2) Click the Picture to Zoom In

  • ARG63144 anti-TRPM7 / LTRPC7 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed U2OS cells permeabilized with 0.15% Triton. Cells were stained with ARG63144 anti-TRPM7 / LTRPC7 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Phalloidin (red) for Actin filaments staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.

  • ARG63144 anti-TRPM7 / LTRPC7 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Mouse Hippocampus. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63144 anti-TRPM7 / LTRPC7 antibody at 4 µg/ml dilution followed by HRP-staining. Similar results were obtained after antigen retrieval at pH9.