ARG44962
anti-TRIM10 antibody
anti-TRIM10 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes TRIM10 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | TRIM10 |
| 抗原物种 | Human |
| 抗原表位 | LEESPTCPLC KEPFRPGSFR PNWQLANVVE NIERLQLVST LGLGEEDVCQ EHGEKIYFFC EDDEMQLCVV CREAGEHATH TMRFLEDAAA PYREQIHKCL KCLRKEREEI QEIQSRENKR |
| 偶联标记 | Un-conjugated |
| 別名 | TRIM10; Tripartite Motif Containing 10; RFB30; HERF1; RNF9; Tripartite Motif-Containing Protein 10; B30-RING Finger Protein; Tripartite Motif-Containing 10; Hematopoietic RING Finger 1; Tripartite Motif Protein 10; Ring Finger Protein 9; RING Finger Protein 9; Zn-Finger Protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UDY6 Human Tripartite motif-containing protein 10 |
|---|---|
| 基因名称 | TRIM10 |
| 全名 | Tripartite Motif Containing 10 |
| 背景介绍 | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity. Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association between TYK2 and IFNAR1. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG44962 anti-TRIM10 antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44962 anti-TRIM10 antibody at 20 µg/mL dilution.
