ARG57532

anti-TRIAD3 antibody

anti-TRIAD3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes TRIAD3
反应物种 Hu, Ms
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 TRIAD3
抗原物种 Mouse
抗原 Synthetic peptide (15 aa) within aa. 120-170 of Mouse TRIAD3.
偶联标记 Un-conjugated
別名 Ubiquitin-conjugating enzyme 7-interacting protein 1; TRIAD3; AI647468; EC 6.3.2.-; F830018F18Rik; AU019462; E3 ubiquitin-protein ligase RNF216; UbcM4-interacting protein 83; Ubce7ip1; C86502; 2810055G22Rik; RING finger protein 216; Triad domain-containing protein 3; UIP83

应用说明

应用建议
应用 推荐稀释比
ICC/IF20 µg/ml
IHC-P10 µg/ml
WB1 - 2 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse heart.
实际分子量 95 kDa

属性

形式 Liquid
纯化 Purified by affinity chromatography.
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 108086 Mouse RNF216

GeneID: 54476 Human RNF216

Swiss-port # P58283 Mouse E3 ubiquitin-protein ligase RNF216

Swiss-port # Q9NWF9 Human E3 ubiquitin-protein ligase RNF216

基因名称 Rnf216
全名 ring finger protein 216
生物功能 Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Promotes TNF and RIP mediated apoptosis (By similarity). [UniProt]
预测分子量 99 kDa
翻译后修饰 Auto-ubiquitinated. [UniProt]

检测图片 (3) Click the Picture to Zoom In

  • ARG57532 anti-TRIAD3 antibody ICC/IF image

    Immunofluorescence: Mouse heart cells stained with ARG57532 anti-TRIAD3 antibody at 20 µg/ml dilution.

  • ARG57532 anti-TRIAD3 antibody IHC-P image

    Immunohistochemistry: Mouse heart stained with ARG57532 anti-TRIAD3 antibody at 10 µg/ml dilution.

  • ARG57532 anti-TRIAD3 antibody WB image

    Western blot: Mouse heart lysate stained with ARG57532 anti-TRIAD3 antibody at 1 and 2 µg/ml dilution.