ARG44595
anti-TREM1 antibody [6B1] (APC)
anti-TREM1 antibody [6B1] (APC) for Flow cytometry and Human
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody recognizes TREM1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 6B1 |
| 同位型 | IgG1 |
| 靶点名称 | TREM1 |
| 抗原物种 | Human |
| 偶联标记 | APC |
| 別名 | TREM1; Triggering Receptor Expressed On Myeloid Cells 1; TREM-1; CD354; Triggering Receptor Expressed On Monocytes 1; CD354 Antigen |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NP99 Human Triggering receptor expressed on myeloid cells 1 |
|---|---|
| 基因名称 | TREM1 |
| 全名 | Triggering Receptor Expressed On Myeloid Cells 1 |
| 背景介绍 | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
| 生物功能 | By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis. [UniProt] |
| 细胞定位 | Cell membrane, Membrane, Secreted. [UniProt] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG44595 anti-TREM1 antibody [6B1] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44595 anti-TREM1 antibody [6B1] (APC) at 10 μl/ 100 μl dilution.
