ARG40250
anti-TRAF7 antibody
anti-TRAF7 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TRAF7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TRAF7 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human TRAF7. |
| 偶联标记 | Un-conjugated |
| 別名 | E3 ubiquitin-protein ligase TRAF7; RING finger and WD repeat-containing protein 1; EC 6.3.2.-; RFWD1; RING finger protein 119; TNF receptor-associated factor 7; RNF119 |
应用说明
| 预测反应性说明 | Human | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse fetal stomach | ||||||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TRAF7 |
| 全名 | TNF receptor-associated factor 7, E3 ubiquitin protein ligase |
| 背景介绍 | Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004] |
| 生物功能 | E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle. [UniProt] |
| 预测分子量 | 75 kDa |
| 翻译后修饰 | Phosphorylated by MAP3K3. Ubiquitinates itself upon phosphorylation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG40250 anti-TRAF7 antibody WB image
Western blot: 25 µg of Mouse fetal stomach lysate stained with ARG40250 anti-TRAF7 antibody.
