ARG64974

anti-TPP1 antibody

anti-TPP1 antibody for Western blot and Human

Cell Biology and Cellular Response antibody; Neuroscience antibody

概述

产品描述 Goat Polyclonal antibody recognizes TPP1
反应物种 Hu
预测物种 Cow, Dog
应用 WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 TPP1
抗原物种 Human
抗原 C-TPSVIRKRYNLTSQD
偶联标记 Un-conjugated
別名 EC 3.4.14.9; TPP-1; Tripeptidyl-peptidase I; GIG1; Lysosomal pepstatin-insensitive protease; SCAR7; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase 1; CLN2; LPIC; Cell growth-inhibiting gene 1 protein; TPP-I

应用说明

应用建议
应用 推荐稀释比
WB0.3 - 1 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 1200 Human TPP1

Swiss-port # O14773 Human Tripeptidyl-peptidase 1

背景介绍 This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
研究领域 Cell Biology and Cellular Response antibody; Neuroscience antibody
预测分子量 61 kDa
翻译后修饰 Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity.

检测图片 (1) Click the Picture to Zoom In

  • ARG64974 anti-TPP1 antibody WB image

    Western blot: 35 µg of Human Placenta lysate stained with ARG64974 anti-TPP1 antibody at 0.3 µg/ml dilution.