ARG63844

anti-TPH2 antibody

anti-TPH2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse

Neuroscience antibody

概述

产品描述 Goat Polyclonal antibody recognizes TPH2
反应物种 Hu, Ms
预测物种 Cow, Dog, Pig
应用 ICC/IF, IHC-P
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 TPH2
抗原物种 Human
抗原 C-NKPNSGKNDDKGNK
偶联标记 Un-conjugated
別名 Tryptophan 5-hydroxylase 2; ADHD7; NTPH; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2; EC 1.14.16.4

应用说明

应用建议
应用 推荐稀释比
ICC/IFAssay - dependent
IHC-P4 - 6 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 121278 Human TPH2

GeneID: 216343 Mouse TPH2

Swiss-port # Q8CGV2 Mouse Tryptophan 5-hydroxylase 2

Swiss-port # Q8IWU9 Human Tryptophan 5-hydroxylase 2

背景介绍 This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008]
研究领域 Neuroscience antibody
预测分子量 56 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG63844 anti-TPH2 antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Brain Stem. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63844 anti-TPH2 antibody at 4 µg/ml dilution followed by HRP-staining.