ARG41790
anti-TPBG / 5T4 antibody
anti-TPBG / 5T4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TPBG / 5T4 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TPBG / 5T4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human TPBG / 5T4. |
| 偶联标记 | Un-conjugated |
| 別名 | 5T4 oncofetal trophoblast glycoprotein; WAIF1; 5T4; Trophoblast glycoprotein; 5T4AG; 5T4 oncofetal antigen; M6P1; 5T4 oncotrophoblast glycoprotein; Wnt-activated inhibitory factor 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Caco-2 | ||||||
| 实际分子量 | ~ 76 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TPBG |
| 全名 | trophoblast glycoprotein |
| 背景介绍 | This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009] |
| 生物功能 | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Highly glycosylated. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG41790 anti-TPBG / 5T4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human uters cancer tissue stained with ARG41790 anti-TPBG / 5T4 antibody.
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ARG41790 anti-TPBG / 5T4 antibody WB image
Western blot: Caco-2 cell lysate stained with ARG41790 anti-TPBG / 5T4 antibody.
