ARG56189
anti-TOX3 antibody [TOX3/1123]
anti-TOX3 antibody [TOX3/1123] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [TOX3/1123] recognizes TOX3 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | TOX3/1123 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | TOX3 |
| 抗原物种 | Human |
| 抗原 | A recombinant fragment (139 amino acid residues around aa 200-400) from the human TOX3 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Trinucleotide repeat-containing gene 9 protein; TNRC9; TOX high mobility group box family member 3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A431 | ||||
| 实际分子量 | ~ 53 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15405 Human TOX high mobility group box family member 3 |
|---|---|
| 基因名称 | TOX3 |
| 全名 | TOX high mobility group box family member 3 |
| 背景介绍 | The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009] |
| 生物功能 | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. [UniProt] |
| 细胞定位 | Cytoplasmic & nuclear |
| 预测分子量 | 63 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56189 anti-TOX3 antibody [TOX3/1123] WB image
Western blot: A431 cell lysate stained with ARG56189 anti-TOX3 antibody [TOX3/1123].
