ARG45678
anti-TOX3 antibody
anti-TOX3 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TOX3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TOX3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human TOX3. |
| 偶联标记 | Un-conjugated |
| 別名 | TOX3; Trinucleotide repeat-containing gene 9 protein; TNRC9; TOX high mobility group box family member 3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 63 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15405 Human TOX high mobility group box family member 3 |
|---|---|
| 基因名称 | TOX3 |
| 全名 | TOX high mobility group box family member 3 |
| 背景介绍 | The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009] |
| 生物功能 | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. [UniProt] |
| 细胞定位 | Cytoplasmic & nuclear. [UniProt] |
| 预测分子量 | 63 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG45678 anti-TOX3 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45678 anti-TOX3 antibody at 5 μg/ml dilution.
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ARG45678 anti-TOX3 antibody WB image
Western blot: A549 and Raji stained with ARG45678 anti-TOX3 antibody at 0.5 μg/ml dilution.
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ARG45678 anti-TOX3 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45678 anti-TOX3 antibody at 1 µg/10^6 cells dilution.
