ARG55388
anti-TNFAIP1 antibody
anti-TNFAIP1 antibody for Western blot and Human,Mouse,Rat
Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TNFAIP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 特异性 | TNFAIP1 antibody is human, mouse and rat reactive. TNFAIP1 antibody is predicted to not cross-react with other TNFAIP proteins. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TNFAIP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (19 aa) within the last 50 aa of Human TNFAIP1. |
| 偶联标记 | Un-conjugated |
| 別名 | BTB/POZ domain-containing protein TNFAIP1; hBACURD2; B61; BTBD34; EDP1; Tumor necrosis factor, alpha-induced protein 1, endothelial; B12; Protein B12; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse Brain Tissue Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TNFAIP1 |
| 全名 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| 背景介绍 | This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008] |
| 生物功能 | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Phosphorylation at Ser-280 by CK2 facilitates the nucleus localization and increases interaction with PCNA. |
检测图片 (1) Click the Picture to Zoom In
-
ARG55388 anti-TNFAIP1 antibody WB image
Western blot: Mouse brain tissue lysate stained with ARG55388 anti-TNFAIP1 antibody at 1 ug/ml dilution.
