ARG63643
anti-TMX1 / TXNDC1 antibody
anti-TMX1 / TXNDC1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes TMX1 / TXNDC1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TMX1 / TXNDC1 |
| 抗原物种 | Human |
| 抗原 | C-RSLGPSLATDKS |
| 偶联标记 | Un-conjugated |
| 別名 | TXNDC; Thioredoxin-related transmembrane protein 1; Thioredoxin domain-containing protein 1; TMX; Transmembrane Trx-related protein; PDIA11; TXNDC1 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H3N1 Human Thioredoxin-related transmembrane protein 1 |
|---|---|
| 基因名称 | TMX1 |
| 全名 | thioredoxin related transmembrane protein 1 |
| 背景介绍 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017] |
| 生物功能 | May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 32 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG63643 anti-TMX1 / TXNDC1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human spleen tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63643 anti-TMX1 / TXNDC1 antibody at 3.8 µg/ml dilution followed by AP-staining.
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ARG63643 anti-TMX1 / TXNDC1 antibody WB image
Western blot: 35 µg of Human liver lysate (protein in RIPA buffer) stained with ARG63643 anti-TMX1 / TXNDC1 antibody at 0.01 µg/ml dilution and incubated at RT for 1 hour.
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ARG63643 anti-TMX1 / TXNDC1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63643 anti-TMX1 / TXNDC1 antibody at 3.75 µg/ml dilution followed by AP-staining.
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ARG63643 anti-TMX1 / TXNDC1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63643 anti-TMX1 / TXNDC1 antibody at 3.75 µg/ml dilution followed by AP-staining.
