ARG59115
anti-TIAM1 antibody
anti-TIAM1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TIAM1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TIAM1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 1518-1554 of Human TIAM1. (ASVDRDLQERLQATSISQRERGRKTLDSHASRMAQLK) |
| 偶联标记 | Un-conjugated |
| 別名 | TIAM-1; T-lymphoma invasion and metastasis-inducing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13009 Human T-lymphoma invasion and metastasis-inducing protein 1 |
|---|---|
| 基因名称 | TIAM1 |
| 全名 | T-cell lymphoma invasion and metastasis 1 |
| 生物功能 | Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration. [UniProt] |
| 细胞定位 | Cell junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the boundary between cells with actin-rich protrusions (By similarity). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. [UniProt] |
| 预测分子量 | 178 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59115 anti-TIAM1 antibody WB image
Western blot: MCF-7 cell lysate stained with ARG59115 anti-TIAM1 antibody at 0.5 µg/ml dilution.
