ARG65312
anti-TIAL1 antibody
anti-TIAL1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes TIAL1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Cow, Dog |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognize both isoforms (NP_003243.1; NP_001029097.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TIAL1 |
| 抗原物种 | Human |
| 抗原 | C-SPEITTEDIKSAFAP |
| 偶联标记 | Un-conjugated |
| 別名 | TCBP; TIAR; TIA-1-related protein; Nucleolysin TIAR |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TIAL1 |
| 全名 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
| 背景介绍 | The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008] |
| 生物功能 | RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. [UniProt] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Phosphorylated by MAPK14 following DNA damage, releasing TIAR from GADD45A mRNA. |
检测图片 (2) Click the Picture to Zoom In
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ARG65312 anti-TIAL1 & TIA antibody WB image
Western Blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65312 anti-TIAL1 antibody at 2 µg/ml dilution.
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ARG65312 anti-TIAL1 & TIA antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Skin. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65312 anti-TIAL1 antibody at 3.8 µg/ml dilution followed by AP-staining.
