ARG44752
anti-THOP1 / Thimet Oligopeptidase antibody
anti-THOP1 / Thimet Oligopeptidase antibody for Immunoprecipitation and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes THOP1 / Thimet Oligopeptidase |
|---|---|
| 反应物种 | Hu |
| 应用 | IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | THOP1 / Thimet Oligopeptidase |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | EP24.15; TOP; Thimet oligopeptidase; MEPD_HUMAN; EC 3.4.24.15; Endopeptidase 24.15; MP78 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | THOP1 |
| 全名 | thimet oligopeptidase 1 |
| 生物功能 | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 79 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG44752 anti-THOP1 / Thimet Oligopeptidase antibody IP image
Immunoprecipitation: K562 lysate immunoprecipitated with 2.5 µg of ARG44752 anti-THOP1 / Thimet Oligopeptidase antibody.
