ARG40049
anti-THOC7 antibody
anti-THOC7 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes THOC7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | THOC7 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-204 of Human THOC7 (NP_079351.2). |
| 偶联标记 | Un-conjugated |
| 別名 | fSAP24; THO complex subunit 7 homolog; NIF3L1-binding protein 1; hTREX30; Functional spliceosome-associated protein 24; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1BP1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat brain, Mouse kidney and Jurkat | ||||
| 实际分子量 | 24 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | THOC7 |
| 全名 | THO complex 7 |
| 生物功能 | Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Nucleus speckle. Note=Interaction with THOC5 is required for nuclear localization. [UniProt] |
| 预测分子量 | 24 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40049 anti-THOC7 antibody WB image
Western blot: 25 µg of Rat brain, Mouse kidney and Jurkat cell lysates stained with ARG40049 anti-THOC7 antibody at 1:3000 dilution.
