ARG22416
anti-TGN46 antibody
anti-TGN46 antibody for ICC/IF,IHC-Frozen sections,Western blot and Human,Primates
概述
| 产品描述 | Sheep Polyclonal antibody recognizes TGN46 This antibody recognizes Trans-Golgi network integral membrane protein 2 (TGOLN2), also known as TGN38 homolog, TGN46, TGN48 or Trans-Golgi network protein TGN51. TGN46 is a 437 amino acid glycoprotein localized to the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network.TGN46 is a heavily glycosylated protein of around 110-120 kDa. Multiple isoforms of TGN46 are generated by alternative splicing difffering in sequence at the C-terminal protion. Sheep anti Human TGN46 antibody is expeced to recognize all identified isoforms. |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | ICC/IF, IHC-Fr, WB |
| 宿主 | Sheep |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TGN46 |
| 抗原物种 | Human |
| 抗原 | Recombinant human TGN46. |
| 偶联标记 | Un-conjugated |
| 別名 | Trans-Golgi network protein TGN51; TGN48; TGN46; TGN51; Trans-Golgi network integral membrane protein 2; TGN38 homolog; TTGN2; TGN38 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-Fr: Fixation with 3% paraformaldehyde or methanol/acetone is recommended. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.02% Sodium azide, 25% Glycerol and 1% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 25% Glycerol and 1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O43493 Human Trans-Golgi network integral membrane protein 2 |
|---|---|
| 基因名称 | TGOLN2 |
| 全名 | trans-golgi network protein 2 |
| 背景介绍 | This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| 生物功能 | May be involved in regulating membrane traffic to and from trans-Golgi network. [UniProt] |
| 预测分子量 | 46 kDa (unmodified). 110-120 kDa (glycosylated) |
