ARG55982
anti-TGF alpha antibody [MF9]
anti-TGF alpha antibody [MF9] for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
产品描述 | Mouse Monoclonal antibody [MF9] recognizes TGF alpha |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | MF9 |
同位型 | IgG1, kappa |
靶点名称 | TGF alpha |
抗原物种 | Rat |
抗原 | Synthetic peptide around 17 aa (C-terminus) of Rat TGF alpha. |
偶联标记 | Un-conjugated |
別名 | ETGF; EGF-like TGF; TFGA; Protransforming growth factor alpha; TGF-alpha; TGF type 1 |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 0.1 mg/ml BSA |
浓度 | 0.2 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Tgfa |
全名 | transforming growth factor, alpha |
背景介绍 | This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
生物功能 | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. [UniProt] |
细胞定位 | Cytoplasmic and secreted |
预测分子量 | 17 kDa |
检测图片 (1) Click the Picture to Zoom In