ARG55983
anti-TGF alpha antibody [1E8-G6]
anti-TGF alpha antibody [1E8-G6] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1E8-G6] recognizes TGF alpha |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1E8-G6 |
| 同位型 | IgM, kappa |
| 靶点名称 | TGF alpha |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 34-43 of Human TGF alpha. |
| 偶联标记 | Un-conjugated |
| 別名 | ETGF; EGF-like TGF; TFGA; Protransforming growth factor alpha; TGF-alpha; TGF type 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | PEG precipitation |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P01135 Human Protransforming growth factor alpha |
|---|---|
| 基因名称 | TGFA |
| 全名 | transforming growth factor, alpha |
| 背景介绍 | This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| 生物功能 | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. [UniProt] |
| 细胞定位 | Cytoplasmic and secreted |
| 预测分子量 | 17 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55983 anti-TGF alpha antibody [1E8-G6] IHC-P image
Immunohistochemistry: Formalin-fixed, paraffin-embedded Human testicular carcinoma stained with ARG55983 anti-TGF alpha antibody [1E8-G6].
