ARG65030
anti-TET2 antibody
anti-TET2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes TET2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Dog |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TET2 |
| 抗原物种 | Human |
| 抗原 | C-PHPQSNNDQQREGSF |
| 偶联标记 | Un-conjugated |
| 別名 | MDS; KIAA1546; EC 1.14.11.n2; Methylcytosine dioxygenase TET2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 224 kDa |
| 翻译后修饰 | May be glycosylated. It is unclear whether interaction with OGT leads to GlcNAcylation. According to a report, it is not GlcNAcylated by OGT (PubMed:23353889). In contrast, another group reports GlcNAcylation by OGT in mouse ortholog. |
检测图片 (1) Click the Picture to Zoom In
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ARG65030 anti-TET2 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Spleen. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65030 anti-TET2 antibody at 4 µg/ml dilution followed by HRP-staining.
