ARG44957
anti-TECPR1 antibody
anti-TECPR1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes TECPR1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | TECPR1 |
| 抗原物种 | Human |
| 抗原表位 | KVWFRRGVNS HNPCGTSWIE MVGEMTMVNV GMNDQVWGIG CEDRAVYFRQ GVTPSELSGK TWKAIIAARE CDRSHSGSSS SLLSAGCFFG DEVRGSGESA PSDTDASSEV ERPGPGQILP AEPLDDSKNA TGNSASGLGA GRTAEDTVED ACPAEGSREA |
| 偶联标记 | Un-conjugated |
| 別名 | TECPR1; Tectonin Beta-Propeller Repeat Containing 1; KIAA1358 Tectonin Beta-Propeller Repeat-Containing Protein 1; DKFZP434B0335; FLJ23419; FLJ90593 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q7Z6L1 Human Tectonin beta-propeller repeat-containing protein 1 |
|---|---|
| 基因名称 | TECPR1 |
| 全名 | Tectonin Beta-Propeller Repeat Containing 1 |
| 背景介绍 | This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy [provided by RefSeq, Nov 2012] |
| 生物功能 | Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns3P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle, Lysosome, Membrane. [UniProt] |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG44957 anti-TECPR1 antibody IHC-P image
Immunohistochemistry: Human colon stained with ARG44957 anti-TECPR1 antibody at 10 µg/mL dilution.
