ARG64393
anti-TCL1A antibody
anti-TCL1A antibody for Western blot and Human
Cancer antibody; Gene Regulation antibody
概述
产品描述 | Goat Polyclonal antibody recognizes TCL1A |
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反应物种 | Hu |
应用 | WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | TCL1A |
抗原物种 | Human |
抗原 | C-QLYPDGRYRSSD |
偶联标记 | Un-conjugated |
別名 | Protein p14 TCL1; Oncogene TCL1; T-cell leukemia/lymphoma protein 1A; TCL1; Oncogene TCL-1 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by antigen affinity chromatography. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P56279 Human T-cell leukemia/lymphoma protein 1A |
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背景介绍 | Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010] |
研究领域 | Cancer antibody; Gene Regulation antibody |
预测分子量 | 13 kDa |
检测图片 (1) Click the Picture to Zoom In