ARG43437
anti-TCIRG1 antibody
anti-TCIRG1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TCIRG1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TCIRG1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-130 of Human TCIRG1 (NP_006010.2). |
| 偶联标记 | Un-conjugated |
| 別名 | V-ATPase 116 kDa isoform a3; Stv1; V-type proton ATPase 116 kDa subunit a isoform 3; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3; ATP6V0A3; OC-116 kDa; ATP6N1C; Vph1; T-cell immune regulator 1; a3; OC116; OPTB1; Atp6i; OC-116kDa; T-cell immune response cDNA7 protein; TIRC7; Osteoclastic proton pump 116 kDa subunit |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13488 Human V-type proton ATPase 116 kDa subunit a isoform 3 |
|---|---|
| 基因名称 | TCIRG1 |
| 全名 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| 背景介绍 | This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, May 2017] |
| 生物功能 | Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation. [UniProt] |
| 细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 93 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG43437 anti-TCIRG1 antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG43437 anti-TCIRG1 antibody at 1:100 dilution.
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ARG43437 anti-TCIRG1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver tissue stained with ARG43437 anti-TCIRG1 antibody at 1:100 dilution.
文献引用
Histochemical assessment of osteoclast-like giant cells in Rankl-/- mice
IHC-P / Mouse
