概述

产品描述	Rabbit Polyclonal antibody recognizes TCEAL1
反应物种	Hu
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	TCEAL1
抗原物种	Human
抗原	KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human TCEAL1.
偶联标记	Un-conjugated
別名	pp21; Transcription elongation factor A protein-like 1; Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1; TCEA-like protein 1; p21; WEX9; SIIR

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	RD

属性

形式	Liquid
纯化	Purification with Protein A and immunogen peptide.
缓冲液	PBS and 0.09% (W/V) Sodium azide
抗菌剂	0.09% (W/V) Sodium azide
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 9338 Human TCEAL1 Swiss-port # Q15170 Human Transcription elongation factor A protein-like 1
基因名称	TCEAL1
全名	transcription elongation factor A (SII)-like 1
背景介绍	This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
生物功能	May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly. [UniProt]
细胞定位	Nucleus.
预测分子量	18 kDa
翻译后修饰	Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.

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