ARG55115
anti-TBX21 / T-bet antibody
anti-TBX21 / T-bet antibody for ELISA,ICC/IF,Western blot and Human,Mouse
Developmental Biology antibody; Gene Regulation antibody; Immune System antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TBX21 / T-bet |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, ICC/IF, WB |
| 特异性 | TBX21 antibody is human and mouse reactive. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TBX21 / T-bet |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (19 aa) within the last 50 aa of Human TBX21 / T-bet protein. |
| 偶联标记 | Un-conjugated |
| 別名 | T-box protein 21; T-box transcription factor TBX21; TBET; T-cell-specific T-box transcription factor T-bet; T-bet; T-PET; TBLYM; Transcription factor TBLYM |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Cat. No. 1210- 293 Cell Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TBX21 |
| 全名 | T-box 21 |
| 背景介绍 | TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. Members of this family include transcription factors involved in the regulation of developmental processes. Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma. Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. |
| 生物功能 | Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. [UniProt] |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody; Immune System antibody |
| 预测分子量 | 58 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55115 anti-TBX21 / T-bet antibody WB image
Western blot: 293 cell lysate stained with ARG55115 anti-TBX21 / T-bet antibody at 1 ug/ml dilution.
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ARG55115 anti-TBX21 / T-bet antibody ICC/IF image
Immunofluorescence: 293 cells stained with ARG55115 anti-TBX21 / T-bet antibody at 5 ug/ml dilution.
