ARG44040
anti-TAX1BP1 antibody
anti-TAX1BP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TAX1BP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TAX1BP1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein of Human TRAF6BP. |
| 偶联标记 | Un-conjugated |
| 別名 | TAX1BP1; Tax1 Binding Protein 1; CALCOCO3; TXBP151; Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1; Tax1-Binding Protein 1; TRAF6-Binding Protein; T6BP |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TAX1BP1 |
| 全名 | Tax1 Binding Protein 1 |
| 背景介绍 | This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation. |
| 细胞定位 | Cytoplasm, Cytoplasmic vesicle, Mitochondrion |
| 预测分子量 | 91 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44040 anti-TAX1BP1 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG44040 anti-TAX1BP1 antibody.
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ARG44040 anti-TAX1BP1 antibody WB image
Western blot: K562 and HeLa stained with ARG44040 anti-TAX1BP1 antibody.
