ARG52436
anti-Synaptotagmin 1 antibody
anti-Synaptotagmin 1 antibody for Western blot and Rat
Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Synaptotagmin 1 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Bov, Chk, NHuPrm |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Synaptotagmin 1 |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide corresponding to amino acid residues specific to synaptotagmin 1 conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | P65; Synaptotagmin I; SytI; SVP65; SYT; p65; Synaptotagmin-1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | Specific for ~65k synaptotagmin I protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SYT1 |
| 全名 | synaptotagmin I |
| 背景介绍 | Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006). |
| 研究领域 | Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 48 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52436 anti-Synaptotagmin 1 antibody WB image
Western blot: Rat cortex lysate showing specific labeling of the ~65k synaptotagmin protein stained with ARG52436 anti-Synaptotagmin 1 antibody.
