ARG52433
anti-Synaptobrevin antibody [SP10]
anti-Synaptobrevin antibody [SP10] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Bovine,Hamster,Pig,Rabbit
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [SP10] recognizes Synaptobrevin |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Hm, Pig, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SP10 |
| 同位型 | IgM |
| 靶点名称 | Synaptobrevin |
| 抗原物种 | Human |
| 抗原 | Synaptic immunoprecipitate (crude) from human brain |
| 偶联标记 | Un-conjugated |
| 別名 | Vesicle-associated membrane protein 1; Synaptobrevin-1; SYB1; VAMP-1; SPAX1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | The antibody is specific for the ~16kDa synaptobrevin protein in Western blots of Rat brain lysate. The antibody has also been demonstRated to work in immunohistochemistry on formalin fixed, vibRatome sections, but does not work on paraffin sections. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | IgM Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | VAMP1/2 |
| 全名 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| 背景介绍 | Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease (Sze et al., 2000). |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 13 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52433 anti-Synaptobrevin antibody [SP10] WB image
Western blot: Rat brain lysate showing specific immunolabeling of the ~ 16k synaptobrevin protein stained with ARG52433 anti-Synaptobrevin antibody [SP10].
