ARG51841

anti-Synapsin 1 phospho (Ser549) antibody

anti-Synapsin 1 phospho (Ser549) antibody for Western blot and Human,Mouse,Rat

Neuroscience antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes Synapsin 1 phospho (Ser549)
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Synapsin 1
抗原物种 Mouse
抗原 Phosphospecific peptide around Ser549 (P-A-S(p)-P-S) of Rat Synapsin 1.
偶联标记 Un-conjugated
別名 SYNI; Brain protein 4.1; Synapsin-1; SYN1a; SYN1b; Synapsin I

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
缓冲液 PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20964 Mouse SYN1

GeneID: 24949 Rat SYN1

GeneID: 6853 Human SYN1

基因名称 Syn1
全名 synapsin I
背景介绍 Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level
生物功能 Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. Regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxide functions at a presynaptic level. [UniProt]
研究领域 Neuroscience antibody
预测分子量 74 kDa
翻译后修饰 Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal.
Phosphorylation at Ser-9 dissociates synapsins from synaptic vesicles.

检测图片 (2) Click the Picture to Zoom In

  • ARG51841 anti-Synapsin 1 phospho (Ser549) antibody WB image

    Western blot: Extracts from Rat brain tissue or calf intestinal phosphatase (CIP), stained with ARG51841 anti-Synapsin 1 phospho (Ser549) antibody.

  • ARG51841 anti-Synapsin 1 phospho (Ser549) antibody WB image

    Western blot: Extract from Rat brain and Mouse brain tissue stained with ARG51841 anti-Synapsin 1 phospho (Ser549) antibody.