ARG56550
anti-Substance P antibody [NC1/34]
anti-Substance P antibody [NC1/34] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat,Rabbit
概述
| 产品描述 | Rat Monoclonal antibody [NC1/34] recognizes Substance P |
|---|---|
| 反应物种 | Hu, Ms, Rat, Rb |
| 预测物种 | Cyfsh, Mamm, Pgn |
| 应用 | ICC/IF, IHC-Fr, IHC-P |
| 特异性 | This antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin; Cross-reactivity with eledoisin: 5%. It recognizes Substance P in postmortem tissue of the human brain. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | NC1/34 |
| 同位型 | IgG2a |
| 靶点名称 | Substance P |
| 抗原物种 | Human |
| 抗原 | Substance P |
| 偶联标记 | Un-conjugated |
| 別名 | NKA; NKNA; NPK; TAC2; Neuromedin L; NK2; PPT; Protachykinin-1; Substance K; Hs.2563 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Rabbit samples have been tested on O.C.T. embedded formaldehyde fixed frozen tissue sections only. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Non Purified. |
| 缓冲液 | Tissue culture supernatant and 0.05% Thimerosal. |
| 抗菌剂 | 0.05% Thimerosal |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TAC1 |
| 全名 | tachykinin, precursor 1 |
| 背景介绍 | This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
| 生物功能 | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. [UniProt] |
| 预测分子量 | 15 kDa |
| 翻译后修饰 | The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). |
