ARG41577
anti-Substance P antibody
anti-Substance P antibody for ICC/IF,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Substance P |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Substance P |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-129 of Human Substance P (NP_003173.1). |
| 偶联标记 | Un-conjugated |
| 別名 | NKA; NKNA; NPK; TAC2; Neuromedin L; NK2; PPT; Protachykinin-1; Substance K; Hs.2563 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | SW620 | ||||||
| 实际分子量 | ~ 19 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TAC1 |
| 全名 | tachykinin, precursor 1 |
| 背景介绍 | This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
| 生物功能 | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 15 kDa |
| 翻译后修饰 | The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41577 anti-Substance P antibody WB image
Western blot: 25 µg of SW620 cell lysate stained with ARG41577 anti-Substance P antibody at 1:1000 dilution.
