ARG43264
anti-Stearoyl-CoA desaturase antibody
anti-Stearoyl-CoA desaturase antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Stearoyl-CoA desaturase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Stearoyl-CoA desaturase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 200 to the C-terminus of Human Stearoyl-CoA desaturase (NP_005054.3). |
| 偶联标记 | Un-conjugated |
| 別名 | Fatty acid desaturase; SCDOS; MSTP008; Acyl-CoA desaturase; SCD1; EC 1.14.19.1; hSCD1; Stearoyl-CoA desaturase; Delta-9 desaturase; Delta; 9; FADS5 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse liver | ||||||||
| 实际分子量 | ~ 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SCD |
| 全名 | stearoyl-CoA desaturase (delta-9-desaturase) |
| 背景介绍 | This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015] |
| 生物功能 | Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 42 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG43264 anti-Stearoyl-CoA desaturase antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43264 anti-Stearoyl-CoA desaturase antibody at 1:100 dilution.
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ARG43264 anti-Stearoyl-CoA desaturase antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG43264 anti-Stearoyl-CoA desaturase antibody at 1:100 dilution.
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ARG43264 anti-Stearoyl-CoA desaturase antibody WB image
Western blot: 25 µg of Mouse liver lysate stained with ARG43264 anti-Stearoyl-CoA desaturase antibody at 1:1000 dilution.
