ARG53612
anti-Stathmin antibody [SP49]
anti-Stathmin antibody [SP49] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Neuroscience antibody; Signaling Transduction antibody

概述
产品描述 | Rabbit Monoclonal antibody [SP49] recognizes Stathmin |
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反应物种 | Hu |
应用 | FACS, IHC-P, WB |
宿主 | Rabbit |
克隆 | Monoclonal |
克隆号 | SP49 |
同位型 | IgG |
靶点名称 | Stathmin |
抗原物种 | Human |
抗原 | Synthetic peptide derived from internal region of human stathmin. |
偶联标记 | Un-conjugated |
別名 | PP17; Prosolin; Stathmin; Protein Pr22; PR22; Lag; C1orf215; PP19; pp19; SMN; OP18; Leukemia-associated phosphoprotein p18; LAP18; pp17; Oncoprotein 18; Phosphoprotein p19; Op18; Metablastin |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Incubation Time: 30 min at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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阳性对照 | Tonsil, NIH/3T3 |
属性
形式 | Liquid |
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纯化 | Purified by protein A/G |
缓冲液 | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
抗菌剂 | < 0.1% Sodium azide |
稳定剂 | 1% BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | STMN1 |
全名 | stathmin 1 |
背景介绍 | This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
生物功能 | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity). [UniProt] |
细胞定位 | Cytoplasm |
研究领域 | Neuroscience antibody; Signaling Transduction antibody |
预测分子量 | 17 kDa |
翻译后修饰 | Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization (By similarity). Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity. |
检测图片 (16) Click the Picture to Zoom In
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ARG53612 anti-Stathmin antibody [SP49] WB image
Western Blot: NIH3T3 stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human B-Cell Lymphoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Pancreatic Adenocarcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Stomach Adenocarcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Thymus stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Tonsil stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Tonsil stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Lymph Node stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Bladder Transitional Cell Carcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Breast Ductal Cell Carcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Cervical Squamous Cell Carcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Colon Adenocarcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Endometrium Adenocarcinoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human HK Lymphoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Melanoma stained with Stathmin antibody [SP49] (ARG53612)
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ARG53612 anti-Stathmin antibody [SP49] IHC-P image
Immunohistochemistry: Human Ovarian Adenocarcinoma stained with Stathmin antibody [SP49] (ARG53612)