ARG52425
anti-Stargazin antibody
anti-Stargazin antibody for Western blot and Rat
Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Stargazin |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Stargazin |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Voltage-dependent calcium channel gamma-2 subunit; TARP gamma-2; Neuronal voltage-gated calcium channel gamma-2 subunit; MRD10; Transmembrane AMPAR regulatory protein gamma-2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | Specific for the ~36k stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CACNG2 |
|---|---|
| 全名 | calcium channel, voltage-dependent, gamma subunit 2 |
| 背景介绍 | Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4. |
检测图片 (1) Click the Picture to Zoom In
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ARG52425 anti-Stargazin antibody WB image
Western Blot: rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein stained with Stargazin antibody (ARG52425).
