ARG58124
anti-Stanniocalcin 2 antibody
anti-Stanniocalcin 2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Stanniocalcin 2 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Stanniocalcin 2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 273-302 (C-terminus) of Human Stanniocalcin 2. |
| 偶联标记 | Un-conjugated |
| 別名 | STC-related protein; Stanniocalcin-2; STC-2; Stanniocalcin-related protein; STCRP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse heart |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | STC2 |
| 全名 | stanniocalcin 2 |
| 背景介绍 | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008] |
| 生物功能 | Has an anti-hypocalcemic action on calcium and phosphate homeostasis. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58124 anti-Stanniocalcin 2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human prostate tissue stained with ARG58124 anti-Stanniocalcin 2 antibody.
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ARG58124 anti-Stanniocalcin 2 antibody WB image
Western blot: 35 µg of Mouse heart lysate stained with ARG58124 anti-Stanniocalcin 2 antibody.
